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MULTISYSTEM DISEASE WITH RENAL INVOLVEMENT: DISORDERS OF PREGNANCY. (3): Hypertension in pregnancy requires careful consideration. Blood pressure usually falls in the first weeks of normal pregnancy and returns to pregestational values only near term. Normal pregnancy is characterized by ECF volume expansion, an increased cardiac output, a decreased systemic vascular resistance, and resistance to the vasopressor effects of angiotensin II. Therefore, any absolute elevation of blood pressure or a pattern of rising blood pressure in early pregnancy is a normal. At least three categories of pregnancy-related hypertension exist. Toxemia is a syndrome of hypertension, proteinuria, hyperuricemia, and edema that is seen in the third trimester of pregnancy. (to be continued . /..) chic wedding selections with ruffle or ruching